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Auburn Hills, MI (Sports Network) - Mitch McGary scored 21 points and grabbed 14 rebounds to power Michigan to a 78-53 rout of VCU in the third round of the NCAA Tournament in front of a partisan crowd at the Palace of Auburn Hills.

Trey Burke added 18 points and seven assists, while Glenn Robinson III and Tim Hardaway Jr. each chipped in 14 points for the Wolverines (28-7), who advanced to the Sweet 16 for the first time since 1994.

Michigan, seeded fourth in the South, will play either Kansas or North Carolina in a potential blockbuster regional semifinal next Friday in Arlington, Texas. The top-seeded Jayhawks and Tar Heels will square off on Sunday in Kansas City.

McGary made 10-of-11 shots to lead a Michigan team that controlled the game inside. Robinson was 7-of-10 from the field and also grabbed nine rebounds. The Wolverines dominated the boards by a 41-24 count.

Juvonte Reddic scored 16 points for VCU (27-9), which played a Big Ten team in the round of 32 for the third straight year. The Rams beat Purdue on the way to a surprising Final Four appearance in 2011 and dropped a two-point decision to Indiana last year.

VCU, coming off an 88-42 demolition of Akron in the second round, struggled all day Saturday, making just 39.7 percent from the field. The swarming Rams defense forced 22 turnovers on Thursday, but turned the Wolverines over just 12 times on Saturday.